| Rank | Player | Team | Goals |
|---|---|---|---|
| 1 |  Yunus Sentamu |  | 16 |
| 2 |  Eric Kambale |  | 15 |
| 3 | Steven Mukwala |  | 14 |
| 4 | Samuel Ssekamatte |  | 12 |
| 5 | Living Kabon |  | 12 |
| 6 | Ben Ocen |  | 11 |
| 7 | Viane Sekajugo |  | 11 |
| 8 | Charles Lwanga |  | 11 |
| 9 | Brian Muruli Mayanja |  | 11 |
| 10 | Joseph Ssemujju |  | 11 |
2020/21 Uganda Premier League top scorers
